Survival Rates of Kidney Cancer


If you have been diagnosed with kidney cancer, your doctor will want to stage your cancer. So you’re going to go through a kidney cancer staging process.
With the staging, doctors are given the chance to reach the survival rates of kidney cancer.

If you have been diagnosed with kidney cancer, your doctor will want to stage your cancer. So, you’re going to go through a kidney cancer staging process.

With the staging of cancer, doctors are given the chance to reach the survival rates of kidney cancer. This means being able to predict a person’s chance of recovery or outlook.
For example, if a patient has been diagnosed with stage 4 kidney cancer, doctors will tell that the survival rate of stage 4 kidney cancer is %8 for a five-year period.

Knowing the survival rates of kidney cancer will allow you to understand your outlook based on the progression of your disease.

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However, the rates given do not always apply to all patients. The situation is unique in each patient.

Because survival rates vary depending on how well you respond to treatment and the risk factors you have.

This means that a late-stage kidney cancer patient who responds well to treatment may live longer than an early-stage kidney cancer patient who responds poorly to treatment.

The staging also means describing how much your cancer has spread and its location, in letters and numbers. This allows your medical team to offer you the best treatment option available.

For more information about the survival rate of Kidney Cancer, you can read:
American Cancer Society: Survival Rates for Kidney Cancer


Kidney cancer staging is performed according to TNM classification.
Therefore, in order to understand staging and survival rates, first of all, classification should be mentioned.

1. Classification of Kidney Cancer

As in many other cancers, kidney cancer is staged with the TNM classification.

In addition to the letters there, some numbers are added to indicate the size of the tumor and whether it is metastasized to lymph nodes or distant organs.

Below you will find detailed information about this classification with the TNM table.

a. Table of TNM Classification

The table below summarizes the TNM classification;

Click to Show/Hide
TNM Characteristics
TXThe primary tumor cannot be assessed (information not available)
T0No evidence of a primary tumor.
T1The tumor is only in the kidney and is no larger than 7 centimeters (cm), or a little less than 3 inches, across.
T1aThe tumor is 4 cm (about 1½ inches) across or smaller and is only in the kidney.
T1bThe tumor is larger than 4 cm but not larger than 7 cm across and is only in the kidney.
T2The tumor is larger than 7 cm across but is still only in the kidney.
T2aThe tumor is more than 7 cm but not more than 10 cm (about 4 inches) across and is only in the kidney.
T2bThe tumor is more than 10 cm across and is only in the kidney.
T3The tumor is growing into a major vein or into tissue around the kidney, but it is not growing into the adrenal gland (on top of the kidney) or beyond Gerota’s fascia (the fibrous layer that surrounds the kidney and nearby fatty tissue).
T3aThe tumor is growing into the main vein leading out of the kidney (renal vein) or into fatty tissue around the kidney.
T3bThe tumor is growing into the part of the large vein leading into the heart (vena cava) that is within the abdomen.
T3cThe tumor has grown into the part of the vena cava that is within the chest or it is growing into the wall of the vena cava.
T4The tumor has spread beyond Gerota’s fascia (the fibrous layer that surrounds the kidney and nearby fatty tissue). The tumor may have grown into the adrenal gland (on top of the kidney).
NXRegional (nearby) lymph nodes cannot be assessed (information not available).
N0No spread to nearby lymph nodes.
N1Tumor has spread to nearby lymph nodes.
M0There is no spread to distant lymph nodes or other orga
M1Distant metastasis is present; includes spread to distant lymph nodes and/or to other organs. Kidney cancer most often spreads to the lungs, bones, liver, or brain.

2. Staging of Kidney Cancer

According to the TNM classification of kidney cancer, it is staged with numbers from 1 to 4.

These stages identify that cancers of the same stage will progress with similar prognosis, also they are treated in a similar way.

At the same time, as a general rule, the lower the stage of kidney cancer, the higher your chance of recovery.

However, as said before, this is not always the case for all people. There are many patient-related, genetic and environmental factors that affect this process.

a. Stage I

Stage 1 kidney cancer is the least aggressive and has the highest 5-year survival rate.

The TNM classification shows that the tumor has relatively small dimensions.

For this reason, it receives the T1 designation.

The tumor was only in one kidney and showed no spread to other organs or lymph nodes. Therefore, it has N0 and M0 designations.

The kidney that develops a tumor in stage 1 is probably surgically removed and usually does not require any treatment afterward. The chances of recovery are extremely high.
In this stage, patients can continue their lives without any problems for a long time.

The five-year survival rate is 81%, this means 81 out of 100 people diagnosed with stage 1 kidney cancer survived for at least 5 years.

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b. Stage II

Stage 2 kidney cancer is more serious than stage 1. At this stage, the tumor is larger than 7 centimeters, but there is no spread to the surrounding organs.

Still, it has N0 and M0 designation since it does not metastasize to lymph nodes or distant organs.

Just like in stage 1, the tumor-developing kidney is likely to be removed with surgery and does not require any treatment after surgery.

For stage 2 kidney cancer, the 5-year survival rate is 74%. This indicates that 74 out of 100 people diagnosed with stage 2 kidney cancer survived for at least 5 years.

c. Stage III

According to TNM classification, stage 3 kidney cancer has two different conditions.

In the first case, the kidney has grown into a major vein and surrounding tissues, and there was no lymph node or distant organ spread.

Second, the size of the tumor can be in any size but it metastatic to the surrounding lymph nodes, but still, there is no distant metastasis. For this condition tumor will have the T1-T3, N1, M0 designation.

In both cases, treatment may be aggressive. If the kidney is metastasized to the lymph nodes, these lymph nodes may need to be surgically removed.

The 5-year survival rate for this stage is 53%. In other words, 53 out of 100 people diagnosed with stage 3 kidney cancer survived for at least 5 years.

d. Stage IV

In stage 4, tumor can be classified in two ways.

For the first case, the tumor has grown into extra-renal tissues. It may or may not be spread to the lymph nodes. However, there is still no distant metastasis. Therefore, the designation, in this case, will be T4, N1-3, M0.

In the other case, the tumor may be of any size and may or may not have spread to the lymph nodes. However, the tumor has metastasized to distant organs.

As a result, the designation of this tumor according to the TNM classification would be T1-4, N1-3, and M1.

The survival rate of stage 4 kidney cancer is 8%. In other words, only 8 out of 100 people with stage 4 kidney cancer survived for at least 5 years after receiving the diagnosis.

e. Table of TNM classification and stages

The table below summarizes the relationship between TNM designations and stages;

Click to Show/Hide
Stage 1Stage 2Stage 3Stage 4
T1, N0, M0×
T1, N0, M1×
T1, N1, M0×
T1, N1, M1×
T2, N0, M0×
T2, N0, M1×
T2, N1, M0×
T2, M1, M1×
T3, N0, M0×
T3, N0, M1×
T3, N1, M0×
T3, N1, M1×
T4, N0, M0×
T4, N0, M1×
T4, N1, M0×
T4, N1, M1×

3. Survival Rates of Kidney Cancer

There are 5-year survival rates for each stage of renal cancer. These survival rate statistics were obtained by observing a large number of patients.

However, it is important to remember that every kidney cancer case is unique. There is no clear effect of numbers on predicting the outlook for each individual.

If you have kidney cancer and have questions about the progression of your disease, be sure to share it with your doctor.

Five-Year Survival Rate for Stage 1 Kidney Cancer81%
Five-Year Survival Rate for Stage 2 Kidney Cancer74%
Five-Year Survival Rate for Stage 3 Kidney Cancer53%
Five-Year Survival Rate for Stage 4 Kidney Cancer8%

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4. Factors That May Affect Staging

Certain factors may reduce survival rates. This is particularly true for stage 3 and stage 4 kidney cancers.

These situations;

  • High lactate dehydrogenase blood level
  • High blood calcium level
  • Low red blood cell count

In addition, some factors that may affect progression can be listed as follows;

  • The spread of cancer to two or more distant organs
  • Need for systemic treatment in less than 1 year after diagnosis of cancer
  • Age
  • Type of treatment

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